For a good street engine with no strip time.
Thinking 42x37 DRD heads, 2276, 10.5:1, 48 IDF's with 40 vents, 1x5/8" exhaust
I ran virtually that exact same spec, only with a 1 3/4" exhaust and it was a really nice drive. Heads were 42x37 044's (hand ported), and I had 10.6:1 - previously had an 86B at IIRC 9.5:1 and it felt so much better with the 86C and the extra compression. Very drivable, I used it daily for a 45 mile commute when my every day car broke.